The 4th International Conference on Fluid Flow and Thermal Science aims to become the leading conference in fields related to fluid flow and heat transfer. The goal of this fluid flow and heat transfer conference 2022 is to provide an online space for scholars from all over the world to present advances in the relevant fields and to foster an environment conducive to exchanging ideas and information. Topics themes for ICFFTS’22 include, but are not limited, to the following: Biofuels Boiling and condensation CFD Combustion Drying Energy optimization Experimental fluid dynamics Flow, heat and mass transfer devices Fuel cells Gas liquid operations Heat transfer augmentation applications Heat transfer enhancement active methods HVAC Laminar and turbulent flows Leaching Mass transfer coefficient Molecular diffusion Nanofluid Non-Newtonian flow Polymer processing Renewable and non-renewable energies Rheology Separation processes